HCSGD entry for SLC1A6

1. General information

Official gene symbolSLC1A6
Entrez ID6511
Gene full namesolute carrier family 1 (high affinity aspartate/glutamate transporter), member 6
Other gene symbolsEAAT4
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003333Amino acid transmembrane transportTASbiological_process
GO:0005313L-glutamate transmembrane transporter activityIEAmolecular_function
GO:0005794Golgi apparatusIEAcellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0005887Integral component of plasma membraneTAScellular_component
GO:0006811Ion transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0015183L-aspartate transmembrane transporter activityTASmolecular_function
GO:0015810Aspartate transportTASbiological_process
GO:0015813L-glutamate transportTASbiological_process
GO:0016020MembraneIEA TAScellular_component
GO:0017153Sodium:dicarboxylate symporter activityIEAmolecular_function
GO:0034220Ion transmembrane transportTASbiological_process
GO:0042391Regulation of membrane potentialIEAbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:1902475L-alpha-amino acid transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.67930471110.74902993430.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1718035587
GSE13712_SHEARDown-0.0103244469
GSE13712_STATICUp0.0207369359
GSE19018Up0.0327956180
GSE19899_A1Up0.0159154602
GSE19899_A2Up0.0228472183
PubMed_21979375_A1Up0.1997347455
PubMed_21979375_A2Down-0.1267155128
GSE35957Up0.1193923025
GSE36640Up0.0275990649
GSE54402Down-0.0550027084
GSE9593Down-0.0171672531
GSE43922Up0.0216358580
GSE24585Down-0.2534262889
GSE37065Up0.0161370580
GSE28863_A1Up0.0063147129
GSE28863_A2Down-0.1908001944
GSE28863_A3Up0.2506693259
GSE28863_A4Up0.1660025354
GSE48662Up0.0326781136

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Glutamic AcidDB00142 NUTR00027

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT028877MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.