HCSGD entry for BMP3
1. General information
| Official gene symbol | BMP3 |
|---|---|
| Entrez ID | 651 |
| Gene full name | bone morphogenetic protein 3 |
| Other gene symbols | BMP-3A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001501 | Skeletal system development | TAS | biological_process |
| GO:0001503 | Ossification | IEA | biological_process |
| GO:0005102 | Receptor binding | TAS | molecular_function |
| GO:0005125 | Cytokine activity | IEA | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0007267 | Cell-cell signaling | TAS | biological_process |
| GO:0008083 | Growth factor activity | IEA | molecular_function |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0040007 | Growth | IEA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
| GO:0051216 | Cartilage development | IEA | biological_process |
| GO:0070700 | BMP receptor binding | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7363070742 | 0.3005635690 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1258355129 |
| GSE13712_SHEAR | Up | 0.0121032021 |
| GSE13712_STATIC | Down | -0.1488885860 |
| GSE19018 | Up | 0.3001369946 |
| GSE19899_A1 | Up | 0.0457598285 |
| GSE19899_A2 | Up | 0.1511988124 |
| PubMed_21979375_A1 | Up | 0.0894011574 |
| PubMed_21979375_A2 | Down | -0.0934026865 |
| GSE35957 | Down | -0.0598111724 |
| GSE36640 | Up | 0.2922678987 |
| GSE54402 | Down | -0.0761519380 |
| GSE9593 | Up | 0.0803311624 |
| GSE43922 | Up | 0.0242729936 |
| GSE24585 | Down | -1.1293148841 |
| GSE37065 | Down | -0.0417094230 |
| GSE28863_A1 | Down | -0.1581725639 |
| GSE28863_A2 | Up | 0.0904002898 |
| GSE28863_A3 | Up | 0.1187990622 |
| GSE28863_A4 | Down | -0.1063013483 |
| GSE48662 | Down | -0.0080660069 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 20027224 | Interestingly, genes that showed the most significant link include those that mediate various signaling pathways implicated in colorectal tumorigenesis, such as BMP3 and BMP6 (BMP signaling), EPHA3, KIT, and FLT1 (receptor tyrosine kinases) and SMO (Hedgehog signaling) |
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