HCSGD entry for RTN4R
1. General information
| Official gene symbol | RTN4R |
|---|---|
| Entrez ID | 65078 |
| Gene full name | reticulon 4 receptor |
| Other gene symbols | NGR NOGOR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004872 | Receptor activity | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007409 | Axonogenesis | NAS | biological_process |
| GO:0009986 | Cell surface | IDA | cellular_component |
| GO:0031225 | Anchored component of membrane | IEA | cellular_component |
| GO:0048011 | Neurotrophin TRK receptor signaling pathway | TAS | biological_process |
| GO:0050770 | Regulation of axonogenesis | TAS | biological_process |
| GO:0050771 | Negative regulation of axonogenesis | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2871044071 | 0.8889209035 | 0.9865372193 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1133598758 |
| GSE13712_SHEAR | Down | -0.4325979159 |
| GSE13712_STATIC | Down | -0.0708776247 |
| GSE19018 | Up | 0.2507761119 |
| GSE19899_A1 | Down | -0.0004456811 |
| GSE19899_A2 | Up | 0.0787814221 |
| PubMed_21979375_A1 | Up | 0.0504511616 |
| PubMed_21979375_A2 | Up | 0.2389079861 |
| GSE35957 | Up | 0.1861229599 |
| GSE36640 | Up | 0.1063177626 |
| GSE54402 | Up | 0.1310168814 |
| GSE9593 | Up | 0.3041515383 |
| GSE43922 | Up | 0.2968340962 |
| GSE24585 | Up | 0.0346126322 |
| GSE37065 | Down | -0.0554517389 |
| GSE28863_A1 | Down | -0.2021321564 |
| GSE28863_A2 | Down | -0.0826601934 |
| GSE28863_A3 | Up | 0.2478464586 |
| GSE28863_A4 | Up | 0.0961229109 |
| GSE48662 | Up | 0.0277642711 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 18836295 | Recently, some studies indicated that coupling special ligand like NGR (N: asparagine, G: glycine, R: arginine) peptide targeting to tumor blood vessels with delivery system can enhance the efficacy of gene transfection |
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