HCSGD entry for SLC1A2

1. General information

Official gene symbolSLC1A2
Entrez ID6506
Gene full namesolute carrier family 1 (glial high affinity glutamate transporter), member 2
Other gene symbolsEAAT2 GLT-1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003333Amino acid transmembrane transportIDAbiological_process
GO:0005313L-glutamate transmembrane transporter activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006811Ion transportTASbiological_process
GO:0007268Synaptic transmissionTASbiological_process
GO:0007632Visual behaviorIEAbiological_process
GO:0009611Response to woundingIEAbiological_process
GO:0010259Multicellular organismal agingIEAbiological_process
GO:0015501Glutamate:sodium symporter activityIEAmolecular_function
GO:0016020MembraneIEA TAScellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0017153Sodium:dicarboxylate symporter activityIEAmolecular_function
GO:0021537Telencephalon developmentIEAbiological_process
GO:0030534Adult behaviorIEAbiological_process
GO:0030673AxolemmaIEAcellular_component
GO:0031668Cellular response to extracellular stimulusIEAbiological_process
GO:0034220Ion transmembrane transportIDAbiological_process
GO:0035264Multicellular organism growthIEAbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0043200Response to amino acidIEAbiological_process
GO:0046326Positive regulation of glucose importIEAbiological_process
GO:0051938L-glutamate importIDAbiological_process
GO:0055085Transmembrane transportTASbiological_process
GO:0070779D-aspartate importIDAbiological_process
GO:1902475L-alpha-amino acid transmembrane transportIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.09761082030.97580946770.65308515511.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1548618607
GSE13712_SHEARUp0.0392420743
GSE13712_STATICDown-0.0638631779
GSE19018Down-0.0115060562
GSE19899_A1Up0.1523788531
GSE19899_A2Up0.1527611862
PubMed_21979375_A1Up0.1582187868
PubMed_21979375_A2Up0.2074396944
GSE35957Up0.1557746846
GSE36640Down-0.2800719129
GSE54402Up0.2994130386
GSE9593Up0.1638735637
GSE43922Up0.2996978354
GSE24585Down-0.0454526186
GSE37065Up0.5224510868
GSE28863_A1Up0.3122137779
GSE28863_A2Up0.5331223138
GSE28863_A3Up0.0559225237
GSE28863_A4Down-0.0093851750
GSE48662Up0.0295945733

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

L-Glutamic AcidDB00142 NUTR00027

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.