HCSGD entry for SIM1
1. General information
| Official gene symbol | SIM1 |
|---|---|
| Entrez ID | 6492 |
| Gene full name | single-minded homolog 1 (Drosophila) |
| Other gene symbols | bHLHe14 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001657 | Ureteric bud development | IEA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0004871 | Signal transducer activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0007399 | Nervous system development | IEA | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1966208731 | 0.7030051138 | 0.8580890749 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0893536202 |
| GSE13712_SHEAR | Up | 0.0326143910 |
| GSE13712_STATIC | Down | -0.1025897368 |
| GSE19018 | Up | 0.0965701701 |
| GSE19899_A1 | Up | 0.0638710731 |
| GSE19899_A2 | Down | -0.0038797758 |
| PubMed_21979375_A1 | Up | 0.1977832275 |
| PubMed_21979375_A2 | Up | 0.0387858765 |
| GSE35957 | Up | 0.0971821353 |
| GSE36640 | Up | 0.1042988775 |
| GSE54402 | Up | 0.0816575507 |
| GSE9593 | Down | -0.2268069674 |
| GSE43922 | Up | 0.0116557312 |
| GSE24585 | Down | -0.3759407875 |
| GSE37065 | Down | -0.1103585592 |
| GSE28863_A1 | Up | 1.0635329940 |
| GSE28863_A2 | Up | 1.1484174559 |
| GSE28863_A3 | Up | 0.0358019981 |
| GSE28863_A4 | Down | -0.2748018325 |
| GSE48662 | Up | 0.1266079942 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
