HCSGD entry for METTL4
1. General information
| Official gene symbol | METTL4 |
|---|---|
| Entrez ID | 64863 |
| Gene full name | methyltransferase like 4 |
| Other gene symbols | HsT661 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0006139 | Nucleobase-containing compound metabolic process | IEA | biological_process |
| GO:0008168 | Methyltransferase activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9694587326 | 0.0065888834 | 0.9999902473 | 0.1636646226 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3803630400 |
| GSE13712_SHEAR | Down | -0.3504440828 |
| GSE13712_STATIC | Down | -0.2631198840 |
| GSE19018 | Up | 0.3458054411 |
| GSE19899_A1 | Down | -0.3624135182 |
| GSE19899_A2 | Down | -2.0542009731 |
| PubMed_21979375_A1 | Up | 0.0389228188 |
| PubMed_21979375_A2 | Down | -1.7467601175 |
| GSE35957 | Down | -0.7814003109 |
| GSE36640 | Down | -0.9277248976 |
| GSE54402 | Down | -0.1877083121 |
| GSE9593 | Down | -0.2405431777 |
| GSE43922 | Down | -0.4590608121 |
| GSE24585 | Down | -0.3042301110 |
| GSE37065 | Up | 0.2534057301 |
| GSE28863_A1 | Down | -0.0262024951 |
| GSE28863_A2 | Down | -0.1647564268 |
| GSE28863_A3 | Down | -0.6243206037 |
| GSE28863_A4 | Up | 0.2280584080 |
| GSE48662 | Up | 0.1509405225 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-197-3p | MIMAT0000227 | MIRT048094 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
