HCSGD entry for PORCN


1. General information

Official gene symbolPORCN
Entrez ID64840
Gene full nameporcupine homolog (Drosophila)
Other gene symbolsDHOF FODH MG61 PORC PPN por
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0009100Glycoprotein metabolic processIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016055Wnt signaling pathwayIEAbiological_process
GO:0016740Transferase activityIEAmolecular_function
GO:0016746Transferase activity, transferring acyl groupsIEAmolecular_function
GO:0030176Integral component of endoplasmic reticulum membraneIEAcellular_component
GO:0032281Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complexIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00660855970.69430941830.21415073711.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3464871260
GSE13712_SHEARDown-1.0130040573
GSE13712_STATICDown-0.3184273283
GSE19018Up0.1263050139
GSE19899_A1Up0.2834375003
GSE19899_A2Up0.8362504366
PubMed_21979375_A1Up1.8470387682
PubMed_21979375_A2Up1.8037119322
GSE35957Down-0.6691786429
GSE36640Up1.3473418648
GSE54402Up0.3942981426
GSE9593Up0.7369147599
GSE43922Up0.9474502237
GSE24585Down-0.2842294535
GSE37065Up0.2899430982
GSE28863_A1Down-0.2456690967
GSE28863_A2Up0.0951989186
GSE28863_A3Down-0.4721672698
GSE28863_A4Up0.2022508959
GSE48662Down-0.0743604807

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT023034MicroarrayFunctional MTI (Weak)18668037
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.