HCSGD entry for KLC2
1. General information
| Official gene symbol | KLC2 |
|---|---|
| Entrez ID | 64837 |
| Gene full name | kinesin light chain 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003777 | Microtubule motor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005829 | Cytosol | ISS TAS | cellular_component |
| GO:0005871 | Kinesin complex | IEA ISS | cellular_component |
| GO:0005874 | Microtubule | IEA | cellular_component |
| GO:0007018 | Microtubule-based movement | TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0008088 | Axon cargo transport | IEA | biological_process |
| GO:0016938 | Kinesin I complex | NAS | cellular_component |
| GO:0019886 | Antigen processing and presentation of exogenous peptide antigen via MHC class II | TAS | biological_process |
| GO:0019894 | Kinesin binding | ISS | molecular_function |
| GO:0035253 | Ciliary rootlet | IEA | cellular_component |
| GO:0043005 | Neuron projection | IEA | cellular_component |
| GO:0043234 | Protein complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0451403062 | 0.8948871168 | 0.4722329094 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1324304510 |
| GSE13712_SHEAR | Up | 0.4434103019 |
| GSE13712_STATIC | Down | -0.0087518354 |
| GSE19018 | Up | 0.0653760349 |
| GSE19899_A1 | Up | 0.0801007766 |
| GSE19899_A2 | Up | 0.8497289147 |
| PubMed_21979375_A1 | Down | -1.1233628703 |
| PubMed_21979375_A2 | Up | 0.8688459172 |
| GSE35957 | Up | 0.0559495665 |
| GSE36640 | Up | 0.3085021728 |
| GSE54402 | Up | 0.6142094881 |
| GSE9593 | Up | 0.2140723585 |
| GSE43922 | Up | 0.5035599663 |
| GSE24585 | Down | -0.3953126836 |
| GSE37065 | Up | 0.0596217634 |
| GSE28863_A1 | Down | -0.0927715497 |
| GSE28863_A2 | Down | -0.1279671904 |
| GSE28863_A3 | Up | 0.3769762656 |
| GSE28863_A4 | Down | -0.0218834519 |
| GSE48662 | Up | 0.2142016458 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-484 | MIMAT0002174 | MIRT042175 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043375 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30c-5p | MIMAT0000244 | MIRT047944 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049334 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
