HCSGD entry for ST3GAL1
1. General information
| Official gene symbol | ST3GAL1 |
|---|---|
| Entrez ID | 6482 |
| Gene full name | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 |
| Other gene symbols | Gal-NAc6S SIAT4A SIATFL ST3GalA ST3GalA.1 ST3GalIA ST3GalIA,1 ST3O |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | TAS | cellular_component |
| GO:0003836 | Beta-galactoside (CMP) alpha-2,3-sialyltransferase activity | IEA ISS | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006054 | N-acetylneuraminate metabolic process | ISS | biological_process |
| GO:0006464 | Cellular protein modification process | TAS | biological_process |
| GO:0006468 | Protein phosphorylation | IEA | biological_process |
| GO:0006486 | Protein glycosylation | IEA | biological_process |
| GO:0006487 | Protein N-linked glycosylation | ISS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016266 | O-glycan processing | TAS | biological_process |
| GO:0018146 | Keratan sulfate biosynthetic process | TAS | biological_process |
| GO:0030173 | Integral component of Golgi membrane | IEA | cellular_component |
| GO:0030203 | Glycosaminoglycan metabolic process | TAS | biological_process |
| GO:0032580 | Golgi cisterna membrane | IEA | cellular_component |
| GO:0042339 | Keratan sulfate metabolic process | TAS | biological_process |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0097503 | Sialylation | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0179765852 | 0.3095074769 | 0.3285426787 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0686528754 |
| GSE13712_SHEAR | Up | 0.5262415112 |
| GSE13712_STATIC | Up | 0.2179317770 |
| GSE19018 | Down | -0.8630317075 |
| GSE19899_A1 | Down | -0.4868428921 |
| GSE19899_A2 | Up | 0.4720218300 |
| PubMed_21979375_A1 | Up | 1.1444707826 |
| PubMed_21979375_A2 | Up | 1.1923486674 |
| GSE35957 | Up | 0.7441953194 |
| GSE36640 | Down | -0.4497956608 |
| GSE54402 | Up | 0.1497344324 |
| GSE9593 | Down | -0.1768825090 |
| GSE43922 | Up | 0.5869710490 |
| GSE24585 | Down | -0.6874194999 |
| GSE37065 | Up | 0.6090945134 |
| GSE28863_A1 | Up | 0.8964494150 |
| GSE28863_A2 | Up | 0.0038237020 |
| GSE28863_A3 | Up | 0.1827965653 |
| GSE28863_A4 | Up | 0.0301886893 |
| GSE48662 | Up | 0.2060530449 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-204-5p | MIMAT0000265 | MIRT047012 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
