HCSGD entry for EXO5

1. General information

Official gene symbolEXO5
Entrez ID64789
Gene full nameexonuclease 5
Other gene symbolsC1orf176 DEM1 Exo V hExo5
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000738DNA catabolic process, exonucleolyticIDAbiological_process
GO:0003677DNA bindingIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005829CytosolIDAcellular_component
GO:0006308DNA catabolic processIDAbiological_process
GO:0008310Single-stranded DNA 3'-5' exodeoxyribonuclease activityTASmolecular_function
GO:0036297Interstrand cross-link repairIMPbiological_process
GO:0042803Protein homodimerization activityTASmolecular_function
GO:0045145Single-stranded DNA 5'-3' exodeoxyribonuclease activityIDAmolecular_function
GO:0046872Metal ion bindingIEAmolecular_function
GO:00515394 iron, 4 sulfur cluster bindingIDAmolecular_function
GO:0090305Nucleic acid phosphodiester bond hydrolysisIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.32432297030.54734671180.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2100107171
GSE13712_SHEARDown-0.1539982040
GSE13712_STATICDown-0.0053932968
GSE19018Down-0.4879356789
GSE19899_A1Up0.1255150580
GSE19899_A2Down-0.1317053457
PubMed_21979375_A1Up0.5261047226
PubMed_21979375_A2Up0.3045613194
GSE35957Down-0.2956467462
GSE36640Down-0.3898922043
GSE54402Down-0.1020329736
GSE9593Down-0.0314662679
GSE43922Up0.2387349596
GSE24585Up0.4587066712
GSE37065Up0.1349387548
GSE28863_A1Down-0.0108455887
GSE28863_A2Up0.3990237750
GSE28863_A3Down-0.1005320320
GSE28863_A4Down-0.0679712534
GSE48662Down-0.3267628600

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.