HCSGD entry for GAREM
1. General information
| Official gene symbol | GAREM |
|---|---|
| Entrez ID | 64762 |
| Gene full name | GRB2 associated, regulator of MAPK1 |
| Other gene symbols | C18orf11 FAM59A Gm944 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | NAS | cellular_component |
| GO:0007173 | Epidermal growth factor receptor signaling pathway | IDA | biological_process |
| GO:0008284 | Positive regulation of cell proliferation | IDA | biological_process |
| GO:0051781 | Positive regulation of cell division | IEA | biological_process |
| GO:0070064 | Proline-rich region binding | IDA | molecular_function |
| GO:0070374 | Positive regulation of ERK1 and ERK2 cascade | IMP | biological_process |
| GO:0071364 | Cellular response to epidermal growth factor stimulus | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0734435052 | 0.7447294366 | 0.5763585271 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1190965272 |
| GSE13712_SHEAR | Down | -0.4262136009 |
| GSE13712_STATIC | Down | -0.1199114201 |
| GSE19018 | Down | -0.0214127997 |
| GSE19899_A1 | Up | 0.4120002896 |
| GSE19899_A2 | Up | 1.1382025346 |
| PubMed_21979375_A1 | Up | 1.0992057819 |
| PubMed_21979375_A2 | Up | 0.2359519627 |
| GSE35957 | Down | -0.2059273384 |
| GSE36640 | Up | 0.0692961933 |
| GSE54402 | Down | -0.1923879387 |
| GSE9593 | Down | -0.0236894817 |
| GSE43922 | Up | 0.5167523397 |
| GSE24585 | Down | -0.0323664054 |
| GSE37065 | Down | -0.0527767236 |
| GSE28863_A1 | Up | 0.4544011894 |
| GSE28863_A2 | Up | 0.0769653908 |
| GSE28863_A3 | Up | 0.1960033604 |
| GSE28863_A4 | Down | -0.1778791479 |
| GSE48662 | Down | -0.0921112130 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-186-5p | MIMAT0000456 | MIRT044938 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
