HCSGD entry for SHB
1. General information
| Official gene symbol | SHB |
|---|---|
| Entrez ID | 6461 |
| Gene full name | Src homology 2 domain containing adaptor protein B |
| Other gene symbols | RP11-3J10.8 bA3J10.2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | IEA | biological_process |
| GO:0005070 | SH3/SH2 adaptor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0009967 | Positive regulation of signal transduction | TAS | biological_process |
| GO:0030154 | Cell differentiation | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6796461381 | 0.4124637856 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1844128198 |
| GSE13712_SHEAR | Down | -0.1378847040 |
| GSE13712_STATIC | Down | -0.1176895059 |
| GSE19018 | Down | -0.0871049408 |
| GSE19899_A1 | Down | -0.2790979664 |
| GSE19899_A2 | Up | 0.2464755140 |
| PubMed_21979375_A1 | Up | 0.0363305310 |
| PubMed_21979375_A2 | Up | 0.5965247788 |
| GSE35957 | Down | -0.1434459280 |
| GSE36640 | Up | 0.0246070949 |
| GSE54402 | Down | -0.1678205916 |
| GSE9593 | Up | 0.0820845636 |
| GSE43922 | Down | -0.0287773770 |
| GSE24585 | Up | 0.4161278543 |
| GSE37065 | Up | 0.0502817153 |
| GSE28863_A1 | Down | -0.0548777783 |
| GSE28863_A2 | Down | -0.0884530435 |
| GSE28863_A3 | Up | 0.0128224169 |
| GSE28863_A4 | Up | 0.0381495650 |
| GSE48662 | Up | 0.0834053097 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-935 | MIMAT0004978 | MIRT036644 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
