HCSGD entry for BNC1


1. General information

Official gene symbolBNC1
Entrez ID646
Gene full namebasonuclin 1
Other gene symbolsBNC BSN1 HsT19447
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003677DNA bindingIEAmolecular_function
GO:0003700Sequence-specific DNA binding transcription factor activityTASmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0006356Regulation of transcription from RNA polymerase I promoterIEAbiological_process
GO:0006357Regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0008284Positive regulation of cell proliferationTASbiological_process
GO:0008544Epidermis developmentTASbiological_process
GO:0042060Wound healingIEAbiological_process
GO:0046872Metal ion bindingIEAmolecular_function
GO:0050679Positive regulation of epithelial cell proliferationIEAbiological_process
GO:0051276Chromosome organizationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.01292058810.09544568220.28380875730.5887569252

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1661936956
GSE13712_SHEARUp0.0732395408
GSE13712_STATICUp0.3549961549
GSE19018Down-0.3490935115
GSE19899_A1Up0.4332039245
GSE19899_A2Up1.0055686141
PubMed_21979375_A1Up3.6698600466
PubMed_21979375_A2Up2.1003719543
GSE35957Down-0.8168940389
GSE36640Down-3.2494000339
GSE54402Up1.0800083689
GSE9593Down-0.1058283829
GSE43922Up1.2122507356
GSE24585Down-0.0146741986
GSE37065Down-0.0104556228
GSE28863_A1Down-0.3059578511
GSE28863_A2Down-1.0188039379
GSE28863_A3Down-0.2384782422
GSE28863_A4Down-0.0045980988
GSE48662Down-0.1565871360

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-335-5pMIMAT0000765MIRT018429MicroarrayFunctional MTI (Weak)18185580
hsa-miR-26b-5pMIMAT0000083MIRT029748MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.