HCSGD entry for SH3GL1
1. General information
| Official gene symbol | SH3GL1 |
|---|---|
| Entrez ID | 6455 |
| Gene full name | SH3-domain GRB2-like 1 |
| Other gene symbols | CNSA1 EEN SH3D2B SH3P8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002102 | Podosome | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0006897 | Endocytosis | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007417 | Central nervous system development | TAS | biological_process |
| GO:0008289 | Lipid binding | IEA | molecular_function |
| GO:0019902 | Phosphatase binding | IEA | molecular_function |
| GO:0030054 | Cell junction | IEA | cellular_component |
| GO:0031901 | Early endosome membrane | IEA | cellular_component |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0042995 | Cell projection | IEA | cellular_component |
| GO:0051020 | GTPase binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5417389005 | 0.1825999772 | 0.9999902473 | 0.8282291918 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0102313528 |
| GSE13712_SHEAR | Down | -0.2949518977 |
| GSE13712_STATIC | Down | -0.1212142770 |
| GSE19018 | Up | 0.0209145160 |
| GSE19899_A1 | Down | -0.1255571956 |
| GSE19899_A2 | Up | 0.3400549254 |
| PubMed_21979375_A1 | Up | 0.5054590085 |
| PubMed_21979375_A2 | Up | 2.2787379995 |
| GSE35957 | Down | -0.2561100293 |
| GSE36640 | Down | -0.2421892103 |
| GSE54402 | Up | 0.4696564874 |
| GSE9593 | Down | -0.1813306739 |
| GSE43922 | Down | -0.0479091724 |
| GSE24585 | Down | -0.2575767887 |
| GSE37065 | Down | -0.3746280392 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.4164746548 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028595 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-320b | MIMAT0005792 | MIRT036218 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-877-5p | MIMAT0004949 | MIRT037377 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037699 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038486 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041509 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044698 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
