HCSGD entry for SH3BP2
1. General information
| Official gene symbol | SH3BP2 |
|---|---|
| Entrez ID | 6452 |
| Gene full name | SH3-domain binding protein 2 |
| Other gene symbols | 3BP-2 3BP2 CRBM CRPM |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005070 | SH3/SH2 adaptor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0009967 | Positive regulation of signal transduction | TAS | biological_process |
| GO:0017124 | SH3 domain binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9691025151 | 0.1098287299 | 0.9999902473 | 0.6345043898 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1212664072 |
| GSE13712_SHEAR | Down | -0.1521385200 |
| GSE13712_STATIC | Down | -0.3026604633 |
| GSE19018 | Down | -0.0588755695 |
| GSE19899_A1 | Down | -0.1278180562 |
| GSE19899_A2 | Down | -0.9338093702 |
| PubMed_21979375_A1 | Down | -0.5832540516 |
| PubMed_21979375_A2 | Down | -0.2865168917 |
| GSE35957 | Up | 0.1194369709 |
| GSE36640 | Down | -0.0159477187 |
| GSE54402 | Up | 0.0936671842 |
| GSE9593 | Down | -0.0288293007 |
| GSE43922 | Down | -0.1344991583 |
| GSE24585 | Down | -0.1844429641 |
| GSE37065 | Down | -0.1593463791 |
| GSE28863_A1 | Up | 0.0768723637 |
| GSE28863_A2 | Up | 0.0945204286 |
| GSE28863_A3 | Up | 0.2610130463 |
| GSE28863_A4 | Down | -0.0960098179 |
| GSE48662 | Down | -0.0084528610 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-939-5p | MIMAT0004982 | MIRT036634 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043409 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-197-3p | MIMAT0000227 | MIRT048121 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
