HCSGD entry for BLVRB

1. General information

Official gene symbolBLVRB
Entrez ID645
Gene full namebiliverdin reductase B (flavin reductase (NADPH))
Other gene symbolsBVRB FLR SDR43U1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004074Biliverdin reductase activityIDAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolIDA TAScellular_component
GO:0005886Plasma membraneIDAcellular_component
GO:0006778Porphyrin-containing compound metabolic processTASbiological_process
GO:0042167Heme catabolic processIDA TASbiological_process
GO:0042602Riboflavin reductase (NADPH) activityIDAmolecular_function
GO:0044281Small molecule metabolic processTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.11583281790.03238655830.69872002750.3389449702

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4722249404
GSE13712_SHEARUp0.0344752402
GSE13712_STATICUp0.5071970025
GSE19018Up0.4761823638
GSE19899_A1Down-0.8338449171
GSE19899_A2Down-1.8648977266
PubMed_21979375_A1Down-1.0184841800
PubMed_21979375_A2Down-1.3923271694
GSE35957Down-0.9427548823
GSE36640Up0.8267132587
GSE54402Down-0.0647848896
GSE9593Up0.7922132887
GSE43922Down-0.8923932975
GSE24585Up0.7849581316
GSE37065Down-0.2619891555
GSE28863_A1Up0.2136270224
GSE28863_A2Down-0.2996585498
GSE28863_A3Down-0.2696400048
GSE28863_A4Up0.1790568028
GSE48662Down-0.2813368064

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

NADHDB00157 NUTR00041 | DB01907 | EXPT02287 | DB03527
Biliverdine Ix AlphaDB02073 EXPT00714
Riboflavin MonophosphateDB03247 EXPT01458
2'-Monophosphoadenosine 5'-DiphosphoriboseDB03461 EXPT02293
7,8-dimethylalloxazineDB04345 EXPT02065
Mesobiliverdin Iv AlphaDB04363 EXPT02129

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-26b-5pMIMAT0000083MIRT029434MicroarrayFunctional MTI (Weak)19088304
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    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.