HCSGD entry for TPSB2

1. General information

Official gene symbolTPSB2
Entrez ID64499
Gene full nametryptase beta 2 (gene/pseudogene)
Other gene symbolsTPS2 tryptaseB tryptaseC
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004252Serine-type endopeptidase activityIEA NASmolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0008236Serine-type peptidase activityTASmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.67348824890.75208301740.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0026245540
GSE13712_SHEARUp0.2020827359
GSE13712_STATICDown-0.0691970721
GSE19018Up0.0534796013
GSE19899_A1Down-0.0880775346
GSE19899_A2Down-0.0729736257
PubMed_21979375_A1Down-0.1140902365
PubMed_21979375_A2Up0.0785786220
GSE35957Down-0.0116206225
GSE36640Up0.1252405294
GSE54402Down-0.0815898867
GSE9593Down-0.1001115202
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1Down-0.1963605066
GSE28863_A2Up0.3249367699
GSE28863_A3Up0.2025060785
GSE28863_A4Up0.1388139580
GSE48662--

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

16436134Tryptase (TPSB2) was expressed at the highest level among all transcripts and its expression level reached a plateau at 8 weeks
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