HCSGD entry for SGSH
1. General information
| Official gene symbol | SGSH |
|---|---|
| Entrez ID | 6448 |
| Gene full name | N-sulfoglucosamine sulfohydrolase |
| Other gene symbols | HSS MPS3A SFMD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA TAS | molecular_function |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0006027 | Glycosaminoglycan catabolic process | TAS | biological_process |
| GO:0006029 | Proteoglycan metabolic process | TAS | biological_process |
| GO:0008484 | Sulfuric ester hydrolase activity | IEA | molecular_function |
| GO:0016250 | N-sulfoglucosamine sulfohydrolase activity | IEA | molecular_function |
| GO:0030203 | Glycosaminoglycan metabolic process | TAS | biological_process |
| GO:0043202 | Lysosomal lumen | TAS | cellular_component |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0116532920 | 0.8856974051 | 0.2718557522 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2786429756 |
| GSE13712_SHEAR | Down | -0.1454453258 |
| GSE13712_STATIC | Up | 0.3219993648 |
| GSE19018 | Down | -0.0710922580 |
| GSE19899_A1 | Down | -0.6591475733 |
| GSE19899_A2 | Up | 0.2877438104 |
| PubMed_21979375_A1 | Up | 0.9124028575 |
| PubMed_21979375_A2 | Up | 1.3756578251 |
| GSE35957 | Up | 0.4311878663 |
| GSE36640 | Up | 2.4618444852 |
| GSE54402 | Down | -0.1006677275 |
| GSE9593 | Up | 0.9318117645 |
| GSE43922 | Down | -0.1963524620 |
| GSE24585 | Up | 0.5958611755 |
| GSE37065 | Down | -0.1625563128 |
| GSE28863_A1 | Up | 0.1315339743 |
| GSE28863_A2 | Up | 0.2843724419 |
| GSE28863_A3 | Up | 0.1311653132 |
| GSE28863_A4 | Up | 0.0650558022 |
| GSE48662 | Up | 0.3621946555 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-941 | MIMAT0004984 | MIRT036568 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30e-3p | MIMAT0000693 | MIRT044118 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30a-3p | MIMAT0000088 | MIRT049918 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
