HCSGD entry for POLR1E
1. General information
| Official gene symbol | POLR1E |
|---|---|
| Entrez ID | 64425 |
| Gene full name | polymerase (RNA) I polypeptide E, 53kDa |
| Other gene symbols | PAF53 PRAF1 RP11-405L18.3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001054 | RNA polymerase I activity | IBA | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003899 | DNA-directed RNA polymerase activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA ISS | cellular_component |
| GO:0005736 | DNA-directed RNA polymerase I complex | IBA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006360 | Transcription from RNA polymerase I promoter | IBA | biological_process |
| GO:0009303 | RRNA transcription | ISS | biological_process |
| GO:0030054 | Cell junction | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3819164393 | 0.0864236275 | 0.9999902473 | 0.5582224049 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0222025869 |
| GSE13712_SHEAR | Down | -0.0580008088 |
| GSE13712_STATIC | Up | 0.4866315425 |
| GSE19018 | Down | -0.9150053367 |
| GSE19899_A1 | Up | 0.0732675294 |
| GSE19899_A2 | Up | 0.1184429414 |
| PubMed_21979375_A1 | Up | 0.9351140762 |
| PubMed_21979375_A2 | Up | 0.3464045750 |
| GSE35957 | Down | -0.0586958967 |
| GSE36640 | Down | -0.8515805969 |
| GSE54402 | Up | 0.4773440374 |
| GSE9593 | Down | -0.3155788035 |
| GSE43922 | Down | -0.0016514577 |
| GSE24585 | Down | -0.6041016655 |
| GSE37065 | Down | -0.5618047994 |
| GSE28863_A1 | Up | 0.3607780748 |
| GSE28863_A2 | Down | -0.1185133222 |
| GSE28863_A3 | Down | -0.1160772859 |
| GSE28863_A4 | Up | 0.1338628125 |
| GSE48662 | Down | -0.3581844794 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
