HCSGD entry for ATG3
1. General information
| Official gene symbol | ATG3 |
|---|---|
| Entrez ID | 64422 |
| Gene full name | autophagy related 3 |
| Other gene symbols | APG3 APG3-LIKE APG3L PC3-96 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000045 | Autophagic vacuole assembly | IEA ISS | biological_process |
| GO:0000153 | Cytoplasmic ubiquitin ligase complex | IPI | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | IDA IEA | cellular_component |
| GO:0006464 | Cellular protein modification process | IDA | biological_process |
| GO:0006612 | Protein targeting to membrane | ISS | biological_process |
| GO:0016567 | Protein ubiquitination | IDA | biological_process |
| GO:0019776 | Atg8 ligase activity | IEA ISS | molecular_function |
| GO:0019777 | Atg12 ligase activity | IEA ISS | molecular_function |
| GO:0019787 | Small conjugating protein ligase activity | IDA | molecular_function |
| GO:0019899 | Enzyme binding | IPI | molecular_function |
| GO:0043653 | Mitochondrial fragmentation involved in apoptotic process | IEA ISS | biological_process |
| GO:1902017 | Regulation of cilium assembly | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9657138863 | 0.0727112116 | 0.9999902473 | 0.5084569075 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2831589419 |
| GSE13712_SHEAR | Down | -0.0404084657 |
| GSE13712_STATIC | Up | 0.0962083002 |
| GSE19018 | Down | -0.2989535586 |
| GSE19899_A1 | Down | -0.3578109404 |
| GSE19899_A2 | Down | -0.4494216968 |
| PubMed_21979375_A1 | Down | -0.6321507778 |
| PubMed_21979375_A2 | Down | -0.2946506310 |
| GSE35957 | Down | -0.2508732457 |
| GSE36640 | Down | -0.2044080351 |
| GSE54402 | Down | -0.0047835822 |
| GSE9593 | Down | -0.0906880736 |
| GSE43922 | Down | -0.4543082172 |
| GSE24585 | Down | -0.0220458793 |
| GSE37065 | Up | 0.2385568966 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.5340953249 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001566 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047709 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
