HCSGD entry for KLHL25
1. General information
| Official gene symbol | KLHL25 |
|---|---|
| Entrez ID | 64410 |
| Gene full name | kelch-like family member 25 |
| Other gene symbols | ENC-2 ENC2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006446 | Regulation of translational initiation | IDA | biological_process |
| GO:0016567 | Protein ubiquitination | IDA | biological_process |
| GO:0031463 | Cul3-RING ubiquitin ligase complex | IDA | cellular_component |
| GO:0042787 | Protein ubiquitination involved in ubiquitin-dependent protein catabolic process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8402014285 | 0.5203962919 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2261316210 |
| GSE13712_SHEAR | Down | -0.0342752793 |
| GSE13712_STATIC | Up | 0.1018026700 |
| GSE19018 | Down | -0.1214905264 |
| GSE19899_A1 | Down | -0.0053172138 |
| GSE19899_A2 | Up | 0.0450013267 |
| PubMed_21979375_A1 | Up | 0.1141189945 |
| PubMed_21979375_A2 | Down | -0.0721977777 |
| GSE35957 | Down | -0.1087661711 |
| GSE36640 | Down | -0.0164634465 |
| GSE54402 | Up | 0.0481388418 |
| GSE9593 | Up | 0.1384582089 |
| GSE43922 | Up | 0.0380025865 |
| GSE24585 | Down | -0.0998010649 |
| GSE37065 | Down | -0.1029261708 |
| GSE28863_A1 | Down | -0.0212330234 |
| GSE28863_A2 | Up | 0.2127335471 |
| GSE28863_A3 | Up | 0.1038440756 |
| GSE28863_A4 | Up | 0.0092865418 |
| GSE48662 | Down | -0.1472443377 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
