HCSGD entry for SFTPD
1. General information
| Official gene symbol | SFTPD |
|---|---|
| Entrez ID | 6441 |
| Gene full name | surfactant protein D |
| Other gene symbols | COLEC7 PSP-D SFTP4 SP-D |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001817 | Regulation of cytokine production | NAS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005581 | Collagen | IEA | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005764 | Lysosome | TAS | cellular_component |
| GO:0006898 | Receptor-mediated endocytosis | TAS | biological_process |
| GO:0007585 | Respiratory gaseous exchange | IEA | biological_process |
| GO:0030139 | Endocytic vesicle | TAS | cellular_component |
| GO:0030246 | Carbohydrate binding | TAS | molecular_function |
| GO:0042130 | Negative regulation of T cell proliferation | TAS | biological_process |
| GO:0042742 | Defense response to bacterium | TAS | biological_process |
| GO:0043129 | Surfactant homeostasis | IMP | biological_process |
| GO:0045085 | Negative regulation of interleukin-2 biosynthetic process | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0048246 | Macrophage chemotaxis | TAS | biological_process |
| GO:0048286 | Lung alveolus development | IMP | biological_process |
| GO:0050766 | Positive regulation of phagocytosis | TAS | biological_process |
| GO:0072593 | Reactive oxygen species metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4075912883 | 0.8462284298 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0170031572 |
| GSE13712_SHEAR | Down | -0.0572649037 |
| GSE13712_STATIC | Up | 0.1750079093 |
| GSE19018 | Up | 0.1523464253 |
| GSE19899_A1 | Up | 0.0943998745 |
| GSE19899_A2 | Down | -0.0913165967 |
| PubMed_21979375_A1 | Up | 0.3245103492 |
| PubMed_21979375_A2 | Down | -0.0636074085 |
| GSE35957 | Up | 0.1293741123 |
| GSE36640 | Up | 0.1212780312 |
| GSE54402 | Up | 0.1592175715 |
| GSE9593 | Up | 0.0370873124 |
| GSE43922 | Up | 0.0269663421 |
| GSE24585 | Up | 0.0621041900 |
| GSE37065 | Down | -0.2903066002 |
| GSE28863_A1 | Down | -0.0610981891 |
| GSE28863_A2 | Down | -0.1182484437 |
| GSE28863_A3 | Up | 0.2907314099 |
| GSE28863_A4 | Up | 0.2000215450 |
| GSE48662 | Up | 0.0083538516 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Beta-D-Glucose | DB02379 | EXPT00685 | EXPT00455 | EXPT01603 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT019062 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
