HCSGD entry for MMP25
1. General information
| Official gene symbol | MMP25 |
|---|---|
| Entrez ID | 64386 |
| Gene full name | matrix metallopeptidase 25 |
| Other gene symbols | MMP-25 MMP20 MMP20A MMPL1 MT-MMP 6 MT-MMP6 MT6-MMP MT6MMP MTMMP6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004222 | Metalloendopeptidase activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005578 | Proteinaceous extracellular matrix | NAS | cellular_component |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006508 | Proteolysis | NAS | biological_process |
| GO:0006954 | Inflammatory response | NAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016020 | Membrane | NAS | cellular_component |
| GO:0031225 | Anchored component of membrane | IEA | cellular_component |
| GO:0060022 | Hard palate development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8014067969 | 0.5640512063 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1868047578 |
| GSE13712_SHEAR | Down | -0.1988099842 |
| GSE13712_STATIC | Down | -0.0304005714 |
| GSE19018 | Up | 0.0546872151 |
| GSE19899_A1 | Down | -0.0563737283 |
| GSE19899_A2 | Up | 0.0892110228 |
| PubMed_21979375_A1 | Down | -0.1613864050 |
| PubMed_21979375_A2 | Up | 0.0450309557 |
| GSE35957 | Down | -0.0951874373 |
| GSE36640 | Up | 0.1143071702 |
| GSE54402 | Up | 0.0753618332 |
| GSE9593 | Down | -0.1488287200 |
| GSE43922 | Up | 0.0889176138 |
| GSE24585 | Up | 0.1496769673 |
| GSE37065 | Down | -0.1110568815 |
| GSE28863_A1 | Down | -0.1682918779 |
| GSE28863_A2 | Down | -0.0408813476 |
| GSE28863_A3 | Up | 0.2939532881 |
| GSE28863_A4 | Up | 0.1150313216 |
| GSE48662 | Up | 0.0000287596 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Marimastat | DB00786 | APRD00559 |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-181c-3p | MIMAT0004559 | MIRT038668 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051134 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
