HCSGD entry for RNF25
1. General information
| Official gene symbol | RNF25 |
|---|---|
| Entrez ID | 64320 |
| Gene full name | ring finger protein 25 |
| Other gene symbols | AO7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004842 | Ubiquitin-protein ligase activity | ISS | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005829 | Cytosol | IDA | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016567 | Protein ubiquitination | ISS | biological_process |
| GO:0051059 | NF-kappaB binding | IPI | molecular_function |
| GO:0051092 | Positive regulation of NF-kappaB transcription factor activity | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0119014323 | 0.8156881577 | 0.2731103749 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6804152110 |
| GSE13712_SHEAR | Up | 0.3405271851 |
| GSE13712_STATIC | Up | 0.1126864229 |
| GSE19018 | Down | -0.3588397502 |
| GSE19899_A1 | Up | 0.1999613694 |
| GSE19899_A2 | Up | 1.2346015970 |
| PubMed_21979375_A1 | Up | 3.0747672547 |
| PubMed_21979375_A2 | Up | 0.8821347943 |
| GSE35957 | Down | -0.2300750082 |
| GSE36640 | Up | 0.3046276882 |
| GSE54402 | Up | 0.5322597011 |
| GSE9593 | Up | 0.0446214472 |
| GSE43922 | Up | 0.6701834961 |
| GSE24585 | Up | 0.3060853732 |
| GSE37065 | Down | -0.1595652729 |
| GSE28863_A1 | Down | -0.4526069979 |
| GSE28863_A2 | Down | -0.0428888255 |
| GSE28863_A3 | Down | -0.3478960634 |
| GSE28863_A4 | Down | -0.1212427048 |
| GSE48662 | Up | 0.0848381891 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-615-3p | MIMAT0003283 | MIRT039726 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
