HCSGD entry for ABCG5

1. General information

Official gene symbolABCG5
Entrez ID64240
Gene full nameATP-binding cassette, sub-family G (WHITE), member 5
Other gene symbolsSTSL
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005524ATP bindingIDA IEAmolecular_function
GO:0005886Plasma membraneTAScellular_component
GO:0006200ATP catabolic processIDAbiological_process
GO:0007584Response to nutrientIEAbiological_process
GO:0007588ExcretionIEA IGIbiological_process
GO:0010212Response to ionizing radiationIEAbiological_process
GO:0010949Negative regulation of intestinal phytosterol absorptionIMPbiological_process
GO:0015918Sterol transportTASbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneIEAcellular_component
GO:0016324Apical plasma membraneIEA IMPcellular_component
GO:0016887ATPase activityIDA IEAmolecular_function
GO:0017127Cholesterol transporter activityIEA IGImolecular_function
GO:0030299Intestinal cholesterol absorptionICbiological_process
GO:0033344Cholesterol effluxIEA IGIbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0042632Cholesterol homeostasisIMPbiological_process
GO:0044281Small molecule metabolic processTASbiological_process
GO:0045796Negative regulation of intestinal cholesterol absorptionIMPbiological_process
GO:0046982Protein heterodimerization activityIPImolecular_function
GO:0055085Transmembrane transportTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.72234635460.83831351010.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0067798916
GSE13712_SHEARUp0.2006493762
GSE13712_STATICDown-0.3347150667
GSE19018Up0.0524343245
GSE19899_A1Up0.0844861551
GSE19899_A2Up0.0927896132
PubMed_21979375_A1Down-0.0760970338
PubMed_21979375_A2Up0.0622977297
GSE35957Up0.0462560050
GSE36640Down-0.1318330168
GSE54402Down-0.0722481680
GSE9593Down-0.0687608216
GSE43922Up0.0153025166
GSE24585Up0.0683524316
GSE37065Down-0.0231750929
GSE28863_A1Up0.0528997474
GSE28863_A2Up0.1852017872
GSE28863_A3Up0.1747371308
GSE28863_A4Up0.0945587974
GSE48662Up0.0085908711

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.