HCSGD entry for ROBO3
1. General information
| Official gene symbol | ROBO3 |
|---|---|
| Entrez ID | 64221 |
| Gene full name | roundabout, axon guidance receptor, homolog 3 (Drosophila) |
| Other gene symbols | HGPPS HGPS RBIG1 RIG1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001764 | Neuron migration | IEA | biological_process |
| GO:0007411 | Axon guidance | IEA NAS TAS | biological_process |
| GO:0016021 | Integral component of membrane | NAS | cellular_component |
| GO:0016199 | Axon midline choice point recognition | ISS | biological_process |
| GO:0030424 | Axon | IEA | cellular_component |
| GO:0042803 | Protein homodimerization activity | IEA | molecular_function |
| GO:0046982 | Protein heterodimerization activity | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8920861593 | 0.0275128984 | 0.9999902473 | 0.3156787271 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1953920496 |
| GSE13712_SHEAR | Down | -1.7857049649 |
| GSE13712_STATIC | Down | -0.4955843519 |
| GSE19018 | Up | 0.5384077044 |
| GSE19899_A1 | Down | -0.2420435735 |
| GSE19899_A2 | Down | -0.0922405098 |
| PubMed_21979375_A1 | Down | -1.2036821280 |
| PubMed_21979375_A2 | Down | -0.4694316770 |
| GSE35957 | Down | -0.5929428456 |
| GSE36640 | Down | -0.7820417331 |
| GSE54402 | Down | -0.3373228410 |
| GSE9593 | Down | -0.2992027588 |
| GSE43922 | Up | 0.1044579699 |
| GSE24585 | Up | 0.0456953706 |
| GSE37065 | Down | -0.0409680493 |
| GSE28863_A1 | Up | 0.1300621874 |
| GSE28863_A2 | Up | 0.0997763581 |
| GSE28863_A3 | Up | 0.3692245338 |
| GSE28863_A4 | Up | 0.1038165749 |
| GSE48662 | Down | -0.1849790681 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022822 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
