HCSGD entry for SEMA4A
1. General information
| Official gene symbol | SEMA4A |
|---|---|
| Entrez ID | 64218 |
| Gene full name | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
| Other gene symbols | CORD10 RP35 SEMAB SEMB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001525 | Angiogenesis | IEA | biological_process |
| GO:0004872 | Receptor activity | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0007409 | Axonogenesis | IEA | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0008360 | Regulation of cell shape | IEA | biological_process |
| GO:0010594 | Regulation of endothelial cell migration | IEA | biological_process |
| GO:0016020 | Membrane | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016525 | Negative regulation of angiogenesis | IEA | biological_process |
| GO:0045063 | T-helper 1 cell differentiation | IEA | biological_process |
| GO:0071526 | Semaphorin-plexin signaling pathway | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7665659245 | 0.7852597584 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0272560652 |
| GSE13712_SHEAR | Down | -0.0043993049 |
| GSE13712_STATIC | Up | 0.0124356786 |
| GSE19018 | Up | 0.0675027859 |
| GSE19899_A1 | Up | 0.0318328181 |
| GSE19899_A2 | Up | 0.1932574998 |
| PubMed_21979375_A1 | Up | 0.1867123398 |
| PubMed_21979375_A2 | Up | 0.2178097958 |
| GSE35957 | Up | 0.1126638442 |
| GSE36640 | Down | -0.0607516287 |
| GSE54402 | Down | -0.0424462792 |
| GSE9593 | Down | -0.0814813862 |
| GSE43922 | Up | 0.0187455711 |
| GSE24585 | Down | -0.0041417396 |
| GSE37065 | Down | -0.1150231328 |
| GSE28863_A1 | Down | -0.2208541582 |
| GSE28863_A2 | Down | -0.0650642308 |
| GSE28863_A3 | Up | 0.1645253260 |
| GSE28863_A4 | Down | -0.0108244471 |
| GSE48662 | Up | 0.1639437912 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
