HCSGD entry for DNAJC1
1. General information
| Official gene symbol | DNAJC1 |
|---|---|
| Entrez ID | 64215 |
| Gene full name | DnaJ (Hsp40) homolog, subfamily C, member 1 |
| Other gene symbols | DNAJL1 ERdj1 HTJ1 MTJ1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001671 | ATPase activator activity | TAS | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA ISS | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0006417 | Regulation of translation | IEA | biological_process |
| GO:0006457 | Protein folding | IEA | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0031965 | Nuclear membrane | IEA | cellular_component |
| GO:0032781 | Positive regulation of ATPase activity | TAS | biological_process |
| GO:0043085 | Positive regulation of catalytic activity | TAS | biological_process |
| GO:0045861 | Negative regulation of proteolysis | TAS | biological_process |
| GO:0050708 | Regulation of protein secretion | IDA | biological_process |
| GO:0050790 | Regulation of catalytic activity | TAS | biological_process |
| GO:0051087 | Chaperone binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0353733255 | 0.9712177463 | 0.4286654236 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.6411047806 |
| GSE13712_SHEAR | Up | 0.2617503243 |
| GSE13712_STATIC | Up | 0.1183390765 |
| GSE19018 | Down | -0.0481189602 |
| GSE19899_A1 | Down | -0.1658792259 |
| GSE19899_A2 | Up | 0.5364085989 |
| PubMed_21979375_A1 | Up | 0.7877523346 |
| PubMed_21979375_A2 | Up | 0.3838777459 |
| GSE35957 | Down | -0.3665278304 |
| GSE36640 | Up | 0.8037738686 |
| GSE54402 | Up | 0.0509138001 |
| GSE9593 | Up | 0.1166445363 |
| GSE43922 | Up | 0.1803899113 |
| GSE24585 | Up | 0.3560136742 |
| GSE37065 | Up | 0.4232277903 |
| GSE28863_A1 | Down | -0.0197922930 |
| GSE28863_A2 | Down | -0.0546843087 |
| GSE28863_A3 | Down | -0.1054758321 |
| GSE28863_A4 | Up | 0.1152419301 |
| GSE48662 | Up | 0.1909456977 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT002721 | Microarray | Functional MTI (Weak) | 15685193 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT002721 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031667 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-let-7b-5p | MIMAT0000063 | MIRT032341 | Proteomics | Functional MTI (Weak) | 18668040 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
