HCSGD entry for LHX5


1. General information

Official gene symbolLHX5
Entrez ID64211
Gene full nameLIM homeobox 5
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003700Sequence-specific DNA binding transcription factor activityIEAmolecular_function
GO:0005634NucleusIEAcellular_component
GO:0006351Transcription, DNA-templatedIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0021527Spinal cord association neuron differentiationIEAbiological_process
GO:0021702Cerebellar Purkinje cell differentiationIEAbiological_process
GO:0021766Hippocampus developmentIEAbiological_process
GO:0021846Cell proliferation in forebrainIEAbiological_process
GO:0021879Forebrain neuron differentiationIEAbiological_process
GO:0021937Cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferationIEAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0045893Positive regulation of transcription, DNA-templatedIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.43127228450.86606598910.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0948734060
GSE13712_SHEARDown-0.1255161571
GSE13712_STATICDown-0.0431292832
GSE19018Up0.1305247737
GSE19899_A1Down-0.0836491813
GSE19899_A2Up0.0514852014
PubMed_21979375_A1Up0.1608675661
PubMed_21979375_A2Up0.1820780892
GSE35957Up0.2579652984
GSE36640Up0.1659784553
GSE54402Up0.1009926481
GSE9593Up0.0970277978
GSE43922Up0.0256974901
GSE24585Down-0.0215326119
GSE37065Down-0.0658682013
GSE28863_A1Down-0.1749913528
GSE28863_A2Down-0.1223717904
GSE28863_A3Up0.4108214244
GSE28863_A4Up0.2132993686
GSE48662Up0.0387284338

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.