HCSGD entry for MMS19
1. General information
| Official gene symbol | MMS19 |
|---|---|
| Entrez ID | 64210 |
| Gene full name | MMS19 nucleotide excision repair homolog (S. cerevisiae) |
| Other gene symbols | MET18 MMS19L hMMS19 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000160 | Phosphorelay signal transduction system | NAS | biological_process |
| GO:0003713 | Transcription coactivator activity | IMP | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA TAS | cellular_component |
| GO:0005675 | Holo TFIIH complex | NAS | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005819 | Spindle | IDA | cellular_component |
| GO:0006259 | DNA metabolic process | IMP | biological_process |
| GO:0006281 | DNA repair | IMP | biological_process |
| GO:0006289 | Nucleotide-excision repair | NAS TAS | biological_process |
| GO:0006351 | Transcription, DNA-templated | NAS | biological_process |
| GO:0006974 | Cellular response to DNA damage stimulus | IMP | biological_process |
| GO:0007059 | Chromosome segregation | IMP | biological_process |
| GO:0009725 | Response to hormone | NAS | biological_process |
| GO:0016226 | Iron-sulfur cluster assembly | IMP | biological_process |
| GO:0030159 | Receptor signaling complex scaffold activity | NAS | molecular_function |
| GO:0030331 | Estrogen receptor binding | IPI | molecular_function |
| GO:0030674 | Protein binding, bridging | NAS | molecular_function |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IMP | biological_process |
| GO:0071817 | MMXD complex | IDA | cellular_component |
| GO:0097361 | CIA complex | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1914009346 | 0.3715908552 | 0.8494122408 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0916080295 |
| GSE13712_SHEAR | Down | -0.4193745307 |
| GSE13712_STATIC | Up | 0.0020922829 |
| GSE19018 | Up | 0.6898388985 |
| GSE19899_A1 | Up | 0.2043186766 |
| GSE19899_A2 | Up | 0.4106556209 |
| PubMed_21979375_A1 | Up | 1.1354993130 |
| PubMed_21979375_A2 | Up | 0.5867212665 |
| GSE35957 | Down | -0.2953935830 |
| GSE36640 | Down | -0.2832949567 |
| GSE54402 | Up | 0.0781931443 |
| GSE9593 | Down | -0.2736017964 |
| GSE43922 | Up | 0.0728086667 |
| GSE24585 | Down | -0.0883561574 |
| GSE37065 | Down | -0.3483154587 |
| GSE28863_A1 | Up | 0.1475750938 |
| GSE28863_A2 | Up | 0.0427421942 |
| GSE28863_A3 | Down | -0.6936545012 |
| GSE28863_A4 | Down | -0.0585441210 |
| GSE48662 | Down | -0.0896296464 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-16-5p | MIMAT0000069 | MIRT005262 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT005262 | Microarray | Functional MTI (Weak) | 21199864 |
| hsa-miR-34a-5p | MIMAT0000255 | MIRT025507 | Proteomics | Functional MTI (Weak) | 21566225 |
| hsa-miR-24-3p | MIMAT0000080 | MIRT030607 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040621 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-29c-3p | MIMAT0000681 | MIRT044232 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
