HCSGD entry for SFPQ
1. General information
| Official gene symbol | SFPQ |
|---|---|
| Entrez ID | 6421 |
| Gene full name | splicing factor proline/glutamine-rich |
| Other gene symbols | POMP100 PSF |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000122 | Negative regulation of transcription from RNA polymerase II promoter | IMP | biological_process |
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000380 | Alternative mRNA splicing, via spliceosome | IMP | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005654 | Nucleoplasm | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006281 | DNA repair | IEA | biological_process |
| GO:0006310 | DNA recombination | IEA | biological_process |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006397 | MRNA processing | TAS | biological_process |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0016363 | Nuclear matrix | IDA | cellular_component |
| GO:0042382 | Paraspeckles | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9914756848 | 0.0034985487 | 0.9999902473 | 0.1202554688 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5036542564 |
| GSE13712_SHEAR | Down | -0.0023812971 |
| GSE13712_STATIC | Down | -0.2070226508 |
| GSE19018 | Down | -0.8731476667 |
| GSE19899_A1 | Down | -0.3545775217 |
| GSE19899_A2 | Down | -0.9557003205 |
| PubMed_21979375_A1 | Down | -1.0296166457 |
| PubMed_21979375_A2 | Down | -0.9972839159 |
| GSE35957 | Down | -0.4177989119 |
| GSE36640 | Down | -0.8814161161 |
| GSE54402 | Down | -0.1943953348 |
| GSE9593 | Down | -0.7818414276 |
| GSE43922 | Down | -0.6130049072 |
| GSE24585 | Down | -0.1100179380 |
| GSE37065 | Down | -0.2777973352 |
| GSE28863_A1 | Up | 0.4236243568 |
| GSE28863_A2 | Up | 0.5721727811 |
| GSE28863_A3 | Down | -0.1659988949 |
| GSE28863_A4 | Down | -0.2194937928 |
| GSE48662 | Down | -0.3695661207 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-141-3p | MIMAT0000432 | MIRT002309 | Immunoprecipitaion//Luciferase reporter assay//Western blot | Functional MTI | 17637574 |
| hsa-miR-29b-3p | MIMAT0000100 | MIRT002310 | Immunoprecipitaion//Luciferase reporter assay//Western blot | Functional MTI | 17637574 |
| hsa-miR-1229-3p | MIMAT0005584 | MIRT036338 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040035 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040650 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041361 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043279 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047727 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
