HCSGD entry for SETMAR
1. General information
| Official gene symbol | SETMAR |
|---|---|
| Entrez ID | 6419 |
| Gene full name | SET domain and mariner transposase fusion gene |
| Other gene symbols | HsMar1 METNASE Mar1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000729 | DNA double-strand break processing | IDA | biological_process |
| GO:0000737 | DNA catabolic process, endonucleolytic | IDA | biological_process |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0004519 | Endonuclease activity | IDA | molecular_function |
| GO:0004803 | Transposase activity | IEA TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IC IEA | cellular_component |
| GO:0005694 | Chromosome | IEA | cellular_component |
| GO:0006313 | Transposition, DNA-mediated | IEA TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0015074 | DNA integration | IEA | biological_process |
| GO:0018024 | Histone-lysine N-methyltransferase activity | IEA | molecular_function |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
| GO:0043566 | Structure-specific DNA binding | IDA TAS | molecular_function |
| GO:0071157 | Negative regulation of cell cycle arrest | IMP | biological_process |
| GO:2001034 | Positive regulation of double-strand break repair via nonhomologous end joining | IDA | biological_process |
| GO:2001251 | Negative regulation of chromosome organization | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9949185175 | 0.0235011550 | 0.9999902473 | 0.2956036772 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0585402430 |
| GSE13712_SHEAR | Down | -0.2368085743 |
| GSE13712_STATIC | Down | -0.0954639555 |
| GSE19018 | Down | -0.2777983600 |
| GSE19899_A1 | Down | -0.1923206402 |
| GSE19899_A2 | Down | -0.3509148813 |
| PubMed_21979375_A1 | Down | -0.2096123069 |
| PubMed_21979375_A2 | Down | -0.6517853458 |
| GSE35957 | Down | -0.0355400759 |
| GSE36640 | Down | -0.7479338269 |
| GSE54402 | Down | -0.2265491430 |
| GSE9593 | Down | -0.3070773008 |
| GSE43922 | Down | -0.2522923924 |
| GSE24585 | Down | -0.3111169946 |
| GSE37065 | Down | -0.0679963686 |
| GSE28863_A1 | Up | 0.2038198931 |
| GSE28863_A2 | Down | -0.3096041809 |
| GSE28863_A3 | Down | -0.1567037395 |
| GSE28863_A4 | Down | -0.0843341953 |
| GSE48662 | Down | -0.1646453430 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
