HCSGD entry for MCCC2
1. General information
| Official gene symbol | MCCC2 |
|---|---|
| Entrez ID | 64087 |
| Gene full name | methylcrotonoyl-CoA carboxylase 2 (beta) |
| Other gene symbols | MCCB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004485 | Methylcrotonoyl-CoA carboxylase activity | IDA NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005739 | Mitochondrion | NAS | cellular_component |
| GO:0005759 | Mitochondrial matrix | TAS | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006552 | Leucine catabolic process | IEA TAS | biological_process |
| GO:0006766 | Vitamin metabolic process | TAS | biological_process |
| GO:0006767 | Water-soluble vitamin metabolic process | TAS | biological_process |
| GO:0006768 | Biotin metabolic process | TAS | biological_process |
| GO:0009083 | Branched-chain amino acid catabolic process | TAS | biological_process |
| GO:0015936 | Coenzyme A metabolic process | IEA | biological_process |
| GO:0016874 | Ligase activity | IEA | molecular_function |
| GO:0034641 | Cellular nitrogen compound metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9743049732 | 0.0381147753 | 0.9999902473 | 0.3679023836 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1795866513 |
| GSE13712_SHEAR | Down | -0.1075414716 |
| GSE13712_STATIC | Up | 0.0131010633 |
| GSE19018 | Down | -0.6595314941 |
| GSE19899_A1 | Down | -0.3780999124 |
| GSE19899_A2 | Down | -0.2035719012 |
| PubMed_21979375_A1 | Down | -0.2125649743 |
| PubMed_21979375_A2 | Down | -0.1037155594 |
| GSE35957 | Down | -0.0756800997 |
| GSE36640 | Down | -0.7778300637 |
| GSE54402 | Up | 0.0050822999 |
| GSE9593 | Down | -0.0964072477 |
| GSE43922 | Down | -0.4943606482 |
| GSE24585 | Down | -0.1599564585 |
| GSE37065 | Down | -0.0317059238 |
| GSE28863_A1 | Up | 0.2379947369 |
| GSE28863_A2 | Up | 0.1384658556 |
| GSE28863_A3 | Down | -0.3283596190 |
| GSE28863_A4 | Down | -0.2110633240 |
| GSE48662 | Down | -0.5724129359 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016273 | Proteomics | Functional MTI (Weak) | 21512034 |
| hsa-miR-769-5p | MIMAT0003886 | MIRT039205 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
