HCSGD entry for MMP27


1. General information

Official gene symbolMMP27
Entrez ID64066
Gene full namematrix metallopeptidase 27
Other gene symbolsMMP-27
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004222Metalloendopeptidase activityIEAmolecular_function
GO:0005509Calcium ion bindingIEAmolecular_function
GO:0005578Proteinaceous extracellular matrixIEAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0030574Collagen catabolic processIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.04300290260.74361316440.46180310081.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0804974617
GSE13712_SHEARUp0.0718681820
GSE13712_STATICUp0.1348795125
GSE19018Up0.3532482967
GSE19899_A1Down-0.0395775290
GSE19899_A2Down-0.2308576193
PubMed_21979375_A1Up0.2606306649
PubMed_21979375_A2Down-0.1487170300
GSE35957Down-0.1165939011
GSE36640Up0.0207962398
GSE54402Down-0.0184771422
GSE9593Down-0.0095371298
GSE43922Up0.0126174828
GSE24585Down-0.1479595013
GSE37065Up0.0044398862
GSE28863_A1Up2.1795525038
GSE28863_A2Up2.0899218777
GSE28863_A3Up0.1086376097
GSE28863_A4Up0.0515711638
GSE48662Down-0.1037897362

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

MarimastatDB00786 APRD00559

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.