HCSGD entry for SELPLG
1. General information
| Official gene symbol | SELPLG |
|---|---|
| Entrez ID | 6404 |
| Gene full name | selectin P ligand |
| Other gene symbols | CD162 CLA PSGL-1 PSGL1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005102 | Receptor binding | NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007155 | Cell adhesion | TAS | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0016020 | Membrane | TAS | cellular_component |
| GO:0016021 | Integral component of membrane | TAS | cellular_component |
| GO:0050900 | Leukocyte migration | TAS | biological_process |
| GO:0050901 | Leukocyte tethering or rolling | IEA | biological_process |
| GO:0050902 | Leukocyte adhesive activation | ISS | biological_process |
| GO:0071354 | Cellular response to interleukin-6 | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8661967516 | 0.1608871130 | 0.9999902473 | 0.7740581140 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0814277226 |
| GSE13712_SHEAR | Down | -0.3623877382 |
| GSE13712_STATIC | Down | -0.0356116266 |
| GSE19018 | Down | -0.1748333006 |
| GSE19899_A1 | Down | -0.1390345607 |
| GSE19899_A2 | Up | 0.4356510218 |
| PubMed_21979375_A1 | Up | 0.1988255695 |
| PubMed_21979375_A2 | Up | 0.1451039354 |
| GSE35957 | Down | -0.0330694544 |
| GSE36640 | Up | 0.5560746013 |
| GSE54402 | Down | -0.1571277463 |
| GSE9593 | Up | 0.2249118234 |
| GSE43922 | Down | -0.0980657224 |
| GSE24585 | Up | 0.0156545233 |
| GSE37065 | Down | -0.1883551388 |
| GSE28863_A1 | Down | -0.3180164181 |
| GSE28863_A2 | Down | -0.1341371316 |
| GSE28863_A3 | Down | -0.5871792212 |
| GSE28863_A4 | Down | -0.1075049292 |
| GSE48662 | Up | 0.0601092284 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT017394 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
