HCSGD entry for BLK
1. General information
| Official gene symbol | BLK |
|---|---|
| Entrez ID | 640 |
| Gene full name | B lymphoid tyrosine kinase |
| Other gene symbols | MODY11 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004713 | Protein tyrosine kinase activity | IEA TAS | molecular_function |
| GO:0004715 | Non-membrane spanning protein tyrosine kinase activity | IDA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0018108 | Peptidyl-tyrosine phosphorylation | IDA TAS | biological_process |
| GO:0032024 | Positive regulation of insulin secretion | IMP | biological_process |
| GO:0035556 | Intracellular signal transduction | TAS | biological_process |
| GO:0050853 | B cell receptor signaling pathway | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5681018122 | 0.8040434976 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0174347895 |
| GSE13712_SHEAR | Down | -0.1491654420 |
| GSE13712_STATIC | Up | 0.0293014402 |
| GSE19018 | Up | 0.1455538892 |
| GSE19899_A1 | Down | -0.1257361568 |
| GSE19899_A2 | Up | 0.1004785655 |
| PubMed_21979375_A1 | Up | 0.0150720173 |
| PubMed_21979375_A2 | Down | -0.0970871339 |
| GSE35957 | Up | 0.0250129485 |
| GSE36640 | Up | 0.1500223993 |
| GSE54402 | Up | 0.0141449439 |
| GSE9593 | Down | -0.0767117639 |
| GSE43922 | Up | 0.1809540693 |
| GSE24585 | Up | 0.1072553091 |
| GSE37065 | Up | 0.0375824682 |
| GSE28863_A1 | Down | -0.1835701428 |
| GSE28863_A2 | Down | -0.0529542470 |
| GSE28863_A3 | Up | 0.1133531070 |
| GSE28863_A4 | Up | 0.3955871490 |
| GSE48662 | Down | -0.0933950484 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
