HCSGD entry for FIGNL1
1. General information
| Official gene symbol | FIGNL1 |
|---|---|
| Entrez ID | 63979 |
| Gene full name | fidgetin-like 1 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000228 | Nuclear chromosome | IDA | cellular_component |
| GO:0000287 | Magnesium ion binding | ISS | molecular_function |
| GO:0001649 | Osteoblast differentiation | IEA ISS | biological_process |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA ISS | cellular_component |
| GO:0005737 | Cytoplasm | IEA ISS | cellular_component |
| GO:0010569 | Regulation of double-strand break repair via homologous recombination | IDA | biological_process |
| GO:0016787 | Hydrolase activity | ISS | molecular_function |
| GO:0017111 | Nucleoside-triphosphatase activity | IEA | molecular_function |
| GO:0033687 | Osteoblast proliferation | IEA ISS | biological_process |
| GO:0043066 | Negative regulation of apoptotic process | IEA ISS | biological_process |
| GO:0046034 | ATP metabolic process | ISS | biological_process |
| GO:0051726 | Regulation of cell cycle | IEA ISS | biological_process |
| GO:0071479 | Cellular response to ionizing radiation | IDA | biological_process |
| GO:2001243 | Negative regulation of intrinsic apoptotic signaling pathway | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6371107139 | 0.0139450173 | 0.9999902473 | 0.2324936829 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0281964710 |
| GSE13712_SHEAR | Up | 0.2034767129 |
| GSE13712_STATIC | Down | -0.3880792733 |
| GSE19018 | Down | -0.8397450502 |
| GSE19899_A1 | Up | 0.0213304040 |
| GSE19899_A2 | Down | -1.4884562064 |
| PubMed_21979375_A1 | Up | 0.0252196881 |
| PubMed_21979375_A2 | Down | -0.4848940666 |
| GSE35957 | Down | -1.7718195909 |
| GSE36640 | Down | -2.7511116537 |
| GSE54402 | Up | 0.2912663159 |
| GSE9593 | Down | -0.5912703106 |
| GSE43922 | Up | 0.0538812386 |
| GSE24585 | Down | -0.0711903839 |
| GSE37065 | Down | -0.0946909517 |
| GSE28863_A1 | Up | 0.0911755635 |
| GSE28863_A2 | Up | 1.0347055449 |
| GSE28863_A3 | Down | -0.0254050548 |
| GSE28863_A4 | Up | 0.0082605295 |
| GSE48662 | Down | -0.6564069365 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-93-5p | MIMAT0000093 | MIRT028035 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
