HCSGD entry for XPNPEP3


1. General information

Official gene symbolXPNPEP3
Entrez ID63929
Gene full nameX-prolyl aminopeptidase (aminopeptidase P) 3, putative
Other gene symbolsAPP3 NPHPL1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003094Glomerular filtrationIMPbiological_process
GO:0004177Aminopeptidase activityIMPmolecular_function
GO:0005739MitochondrionIDA IEAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0008237Metallopeptidase activityIEAmolecular_function
GO:0016485Protein processingIMPbiological_process
GO:0030145Manganese ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.53208267920.61227940810.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1384800156
GSE13712_SHEARUp0.0024093070
GSE13712_STATICUp0.0464323936
GSE19018Down-0.0514827589
GSE19899_A1Up0.0889317505
GSE19899_A2Up0.2350680221
PubMed_21979375_A1Up0.3196087862
PubMed_21979375_A2Up0.0478400379
GSE35957Down-0.2681074620
GSE36640Up0.0396414309
GSE54402Up0.1338961133
GSE9593Down-0.1275032437
GSE43922Up0.1962775635
GSE24585Up0.0114320632
GSE37065Down-0.2112229219
GSE28863_A1Up0.0378287405
GSE28863_A2Down-0.1851422298
GSE28863_A3Down-0.8324598787
GSE28863_A4Up0.1140711437
GSE48662Up0.1478900697

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

    • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT003767MicroarrayFunctional MTI (Weak)15685193
hsa-miR-16-5pMIMAT0000069MIRT031703ProteomicsFunctional MTI (Weak)18668040
hsa-miR-191-3pMIMAT0001618MIRT042395CLASHFunctional MTI (Weak)23622248
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    • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-1MIMAT0000416NAhsa-miR-115685193
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.