HCSGD entry for SDHC
1. General information
| Official gene symbol | SDHC |
|---|---|
| Entrez ID | 6391 |
| Gene full name | succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa |
| Other gene symbols | CYB560 CYBL PGL3 QPS1 SDH3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000104 | Succinate dehydrogenase activity | IEA | molecular_function |
| GO:0005739 | Mitochondrion | TAS | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | ISS TAS | cellular_component |
| GO:0005749 | Mitochondrial respiratory chain complex II | ISS | cellular_component |
| GO:0006099 | Tricarboxylic acid cycle | IEA TAS | biological_process |
| GO:0009055 | Electron carrier activity | IEA | molecular_function |
| GO:0009060 | Aerobic respiration | TAS | biological_process |
| GO:0016021 | Integral component of membrane | TAS | cellular_component |
| GO:0020037 | Heme binding | ISS | molecular_function |
| GO:0022904 | Respiratory electron transport chain | TAS | biological_process |
| GO:0044237 | Cellular metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0045273 | Respiratory chain complex II | TAS | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0055114 | Oxidation-reduction process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4968822081 | 0.6836845865 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2438674580 |
| GSE13712_SHEAR | Down | -0.1948467139 |
| GSE13712_STATIC | Down | -0.1277919041 |
| GSE19018 | Up | 0.0410446999 |
| GSE19899_A1 | Down | -0.0495095752 |
| GSE19899_A2 | Up | 0.0614413412 |
| PubMed_21979375_A1 | Down | -0.2477416104 |
| PubMed_21979375_A2 | Down | -0.1297157656 |
| GSE35957 | Up | 0.2252633905 |
| GSE36640 | Up | 0.2695562721 |
| GSE54402 | Up | 0.0323204018 |
| GSE9593 | Up | 0.3224804365 |
| GSE43922 | Down | -0.0159723254 |
| GSE24585 | Up | 0.0491427245 |
| GSE37065 | Up | 0.1362505874 |
| GSE28863_A1 | Up | 0.1878012410 |
| GSE28863_A2 | Up | 0.1920787477 |
| GSE28863_A3 | Down | -0.4036801289 |
| GSE28863_A4 | Down | -0.2064285443 |
| GSE48662 | Up | 0.2015178501 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| 2-Hexyloxy-6-Hydroxymethyl-Tetrahydro-Pyran-3,4,5-Triol | DB04141 | EXPT00697 |
| UBIQUINONE-1 | DB08689 | - |
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-7-5p | MIMAT0000252 | MIRT025841 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036997 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT040069 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044536 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
