HCSGD entry for SDCBP
1. General information
| Official gene symbol | SDCBP |
|---|---|
| Entrez ID | 6386 |
| Gene full name | syndecan binding protein (syntenin) |
| Other gene symbols | MDA-9 ST1 SYCL TACIP18 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001948 | Glycoprotein binding | IEA | molecular_function |
| GO:0005109 | Frizzled binding | IPI | molecular_function |
| GO:0005137 | Interleukin-5 receptor binding | ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | NAS | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005856 | Cytoskeleton | NAS | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0005895 | Interleukin-5 receptor complex | ISS | cellular_component |
| GO:0005912 | Adherens junction | NAS | cellular_component |
| GO:0005925 | Focal adhesion | IEA | cellular_component |
| GO:0006612 | Protein targeting to membrane | NAS | biological_process |
| GO:0006930 | Substrate-dependent cell migration, cell extension | NAS | biological_process |
| GO:0007265 | Ras protein signal transduction | IEA | biological_process |
| GO:0007268 | Synaptic transmission | NAS | biological_process |
| GO:0007411 | Axon guidance | TAS | biological_process |
| GO:0008022 | Protein C-terminus binding | IEA | molecular_function |
| GO:0008093 | Cytoskeletal adaptor activity | NAS | molecular_function |
| GO:0016020 | Membrane | NAS | cellular_component |
| GO:0019838 | Growth factor binding | IEA | molecular_function |
| GO:0030036 | Actin cytoskeleton organization | NAS | biological_process |
| GO:0035556 | Intracellular signal transduction | NAS | biological_process |
| GO:0042043 | Neurexin family protein binding | IEA | molecular_function |
| GO:0042327 | Positive regulation of phosphorylation | IDA | biological_process |
| GO:0042470 | Melanosome | IEA | cellular_component |
| GO:0042802 | Identical protein binding | IPI | molecular_function |
| GO:0042803 | Protein homodimerization activity | IEA | molecular_function |
| GO:0045545 | Syndecan binding | IPI NAS | molecular_function |
| GO:0046330 | Positive regulation of JNK cascade | IC | biological_process |
| GO:0046875 | Ephrin receptor binding | IEA | molecular_function |
| GO:0046982 | Protein heterodimerization activity | IPI | molecular_function |
| GO:0047485 | Protein N-terminus binding | IPI | molecular_function |
| GO:0050839 | Cell adhesion molecule binding | IEA | molecular_function |
| GO:0070062 | Extracellular vesicular exosome | IDA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0396972531 | 0.9503609399 | 0.4479646101 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3339667282 |
| GSE13712_SHEAR | Up | 0.0114712593 |
| GSE13712_STATIC | Down | -0.0871754928 |
| GSE19018 | Up | 0.2078286931 |
| GSE19899_A1 | Up | 0.6157504738 |
| GSE19899_A2 | Up | 0.5652272628 |
| PubMed_21979375_A1 | Up | 0.4915044164 |
| PubMed_21979375_A2 | Up | 0.6310614522 |
| GSE35957 | Up | 0.0181177696 |
| GSE36640 | Up | 0.2835494287 |
| GSE54402 | Up | 0.2535724512 |
| GSE9593 | Up | 0.3979752663 |
| GSE43922 | Up | 0.0935883244 |
| GSE24585 | Up | 0.2117373118 |
| GSE37065 | Up | 0.1800404077 |
| GSE28863_A1 | Up | 0.0520916943 |
| GSE28863_A2 | Up | 0.4731211041 |
| GSE28863_A3 | Down | -0.3793931795 |
| GSE28863_A4 | Down | -0.1782929647 |
| GSE48662 | Down | -0.5643097010 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001503 | pSILAC//Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT001503 | Reporter assay;Other | Non-Functional MTI | 20584899 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027019 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028447 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-26a-5p | MIMAT0000082 | MIRT050190 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
