HCSGD entry for SRR

1. General information

Official gene symbolSRR
Entrez ID63826
Gene full nameserine racemase
Other gene symbolsILV1 ISO1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000287Magnesium ion bindingIDA IEAmolecular_function
GO:0003941L-serine ammonia-lyase activityIDAmolecular_function
GO:0005509Calcium ion bindingIEA ISSmolecular_function
GO:0005524ATP bindingIDA IEA ISSmolecular_function
GO:0005737CytoplasmIDA IEAcellular_component
GO:0005886Plasma membraneIEAcellular_component
GO:0006520Cellular amino acid metabolic processIEAbiological_process
GO:0006563L-serine metabolic processIDA IEAbiological_process
GO:0007420Brain developmentIEAbiological_process
GO:0007568AgingIEAbiological_process
GO:0008721D-serine ammonia-lyase activityIEAmolecular_function
GO:0009069Serine family amino acid metabolic processISSbiological_process
GO:0016594Glycine bindingIEA ISSmolecular_function
GO:0018114Threonine racemase activityIEA ISSmolecular_function
GO:0030165PDZ domain bindingIPImolecular_function
GO:0030170Pyridoxal phosphate bindingIDA IEA ISSmolecular_function
GO:0030378Serine racemase activityIDA IEAmolecular_function
GO:0032496Response to lipopolysaccharideIEPbiological_process
GO:0042493Response to drugIEAbiological_process
GO:0042803Protein homodimerization activityIDA IEA IPImolecular_function
GO:0042866Pyruvate biosynthetic processIDAbiological_process
GO:0043025Neuronal cell bodyIDAcellular_component
GO:0043278Response to morphineIEAbiological_process
GO:0045177Apical part of cellIEAcellular_component
GO:0051289Protein homotetramerizationIEA ISSbiological_process
GO:0070178D-serine metabolic processIDAbiological_process
GO:0070179D-serine biosynthetic processIDA IEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.97124904450.00932670110.99999024730.1905963509

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3019134446
GSE13712_SHEARDown-0.5168812347
GSE13712_STATICDown-0.2438795492
GSE19018Down-0.4918418706
GSE19899_A1Down-0.2657863779
GSE19899_A2Down-0.4591413522
PubMed_21979375_A1Down-0.0598779857
PubMed_21979375_A2Down-1.3377737117
GSE35957Up0.1190435003
GSE36640Down-0.6716277095
GSE54402Down-0.0289671103
GSE9593Down-0.1827053116
GSE43922Down-1.5741248579
GSE24585Up0.7662456817
GSE37065Down-0.0896202352
GSE28863_A1Down-0.0898931501
GSE28863_A2Down-0.1904464655
GSE28863_A3Down-0.4641100731
GSE28863_A4Up0.1195019660
GSE48662Down-0.2233464134

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.