HCSGD entry for CXCL6
1. General information
| Official gene symbol | CXCL6 |
|---|---|
| Entrez ID | 6372 |
| Gene full name | chemokine (C-X-C motif) ligand 6 |
| Other gene symbols | CKA-3 GCP-2 GCP2 SCYB6 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0006935 | Chemotaxis | TAS | biological_process |
| GO:0006954 | Inflammatory response | TAS | biological_process |
| GO:0006955 | Immune response | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007267 | Cell-cell signaling | TAS | biological_process |
| GO:0008009 | Chemokine activity | IEA | molecular_function |
| GO:0008201 | Heparin binding | IEA | molecular_function |
| GO:0060326 | Cell chemotaxis | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0000187417 | 0.7973946431 | 0.0146500000 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.4442090992 |
| GSE13712_SHEAR | Up | 4.0398926915 |
| GSE13712_STATIC | Up | 2.0834157478 |
| GSE19018 | Down | -0.1256677621 |
| GSE19899_A1 | Up | 4.5113058119 |
| GSE19899_A2 | Up | 6.5325264256 |
| PubMed_21979375_A1 | Up | 4.1998622094 |
| PubMed_21979375_A2 | Up | 6.2560427565 |
| GSE35957 | Down | -0.2038268655 |
| GSE36640 | Down | -0.1770470458 |
| GSE54402 | Up | 1.0600677099 |
| GSE9593 | Down | -1.6026562187 |
| GSE43922 | Up | 0.1039781215 |
| GSE24585 | Up | 0.1116121436 |
| GSE37065 | Up | 1.8232367629 |
| GSE28863_A1 | Up | 0.8306886418 |
| GSE28863_A2 | Up | 0.0968900829 |
| GSE28863_A3 | Up | 1.1219236927 |
| GSE28863_A4 | Down | -0.2826005427 |
| GSE48662 | Down | -0.3608083339 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029714 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
