HCSGD entry for SCN3A
1. General information
| Official gene symbol | SCN3A |
|---|---|
| Entrez ID | 6328 |
| Gene full name | sodium channel, voltage-gated, type III, alpha subunit |
| Other gene symbols | NAC3 Nav1.3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001518 | Voltage-gated sodium channel complex | IEA | cellular_component |
| GO:0005216 | Ion channel activity | IEA | molecular_function |
| GO:0005248 | Voltage-gated sodium channel activity | IEA NAS | molecular_function |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006814 | Sodium ion transport | NAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0034220 | Ion transmembrane transport | NAS | biological_process |
| GO:0035725 | Sodium ion transmembrane transport | NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1198126059 | 0.5497791801 | 0.7085121546 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1881824834 |
| GSE13712_SHEAR | Up | 0.0074823369 |
| GSE13712_STATIC | Down | -0.2237759551 |
| GSE19018 | Down | -0.3319674644 |
| GSE19899_A1 | Down | -0.0677716526 |
| GSE19899_A2 | Down | -0.1955863825 |
| PubMed_21979375_A1 | Down | -0.1906388749 |
| PubMed_21979375_A2 | Down | -0.0845032853 |
| GSE35957 | Up | 1.2603065295 |
| GSE36640 | Up | 1.8516843225 |
| GSE54402 | Down | -0.3073531204 |
| GSE9593 | Up | 0.0196549551 |
| GSE43922 | Up | 0.0146120580 |
| GSE24585 | Up | 0.4744826295 |
| GSE37065 | Up | 0.1553687699 |
| GSE28863_A1 | Up | 0.0127140150 |
| GSE28863_A2 | Up | 0.1388652325 |
| GSE28863_A3 | Up | 0.0404552649 |
| GSE28863_A4 | Up | 0.0013583678 |
| GSE48662 | Up | 1.1850112596 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018072 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-124-3p | MIMAT0000422 | MIRT022759 | Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-1 | MIMAT0000416 | MIRT023856 | Microarray | Functional MTI (Weak) | 18668037 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
