HCSGD entry for SERPINB4
1. General information
| Official gene symbol | SERPINB4 |
|---|---|
| Entrez ID | 6318 |
| Gene full name | serpin peptidase inhibitor, clade B (ovalbumin), member 4 |
| Other gene symbols | LEUPIN PI11 SCCA-2 SCCA1 SCCA2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004867 | Serine-type endopeptidase inhibitor activity | IBA NAS | molecular_function |
| GO:0005576 | Extracellular region | IBA | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0010466 | Negative regulation of peptidase activity | IDA | biological_process |
| GO:0010951 | Negative regulation of endopeptidase activity | IBA | biological_process |
| GO:0030162 | Regulation of proteolysis | IBA NAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0001785456 | 0.9872410585 | 0.0393008264 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3325332493 |
| GSE13712_SHEAR | Down | -0.1968210724 |
| GSE13712_STATIC | Down | -0.0929730371 |
| GSE19018 | Up | 0.1343664276 |
| GSE19899_A1 | Up | 0.8764192280 |
| GSE19899_A2 | Up | 7.0647220482 |
| PubMed_21979375_A1 | Up | 4.5738051727 |
| PubMed_21979375_A2 | Up | 6.0267844483 |
| GSE35957 | Up | 0.4108370578 |
| GSE36640 | Up | 0.1329605908 |
| GSE54402 | Up | 3.5313208214 |
| GSE9593 | Down | -0.0482828390 |
| GSE43922 | Up | 3.9994630357 |
| GSE24585 | Down | -0.2260823300 |
| GSE37065 | Up | 0.6796059468 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0366003430 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirTarBase
- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
