HCSGD entry for ATXN7
1. General information
| Official gene symbol | ATXN7 |
|---|---|
| Entrez ID | 6314 |
| Gene full name | ataxin 7 |
| Other gene symbols | ADCAII OPCA3 SCA7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000226 | Microtubule cytoskeleton organization | IMP | biological_process |
| GO:0003682 | Chromatin binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA IEA | cellular_component |
| GO:0006351 | Transcription, DNA-templated | IEA | biological_process |
| GO:0006997 | Nucleus organization | TAS | biological_process |
| GO:0007601 | Visual perception | TAS | biological_process |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0015630 | Microtubule cytoskeleton | IDA | cellular_component |
| GO:0016363 | Nuclear matrix | IEA | cellular_component |
| GO:0016578 | Histone deubiquitination | IDA | biological_process |
| GO:0042326 | Negative regulation of phosphorylation | IEA | biological_process |
| GO:0043569 | Negative regulation of insulin-like growth factor receptor signaling pathway | IEA | biological_process |
| GO:0045944 | Positive regulation of transcription from RNA polymerase II promoter | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.7697743931 | 0.2477550397 | 0.9999902473 | 0.9574453678 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.5700590290 |
| GSE13712_SHEAR | Up | 0.4142117642 |
| GSE13712_STATIC | Up | 0.4416615877 |
| GSE19018 | Up | 0.0578657943 |
| GSE19899_A1 | Down | -0.0413859722 |
| GSE19899_A2 | Down | -0.0913065097 |
| PubMed_21979375_A1 | Down | -0.2603837246 |
| PubMed_21979375_A2 | Down | -0.0485029368 |
| GSE35957 | Down | -0.1230602979 |
| GSE36640 | Down | -0.3793836961 |
| GSE54402 | Down | -0.0301080173 |
| GSE9593 | Down | -0.2387917476 |
| GSE43922 | Down | -0.0764571399 |
| GSE24585 | Up | 0.0419137669 |
| GSE37065 | Up | 0.2184166575 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.0632591464 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-192-5p | MIMAT0000222 | MIRT004157 | Microarray | Functional MTI (Weak) | 16822819 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT016681 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-342-3p | MIMAT0000753 | MIRT043675 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049634 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050978 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
