HCSGD entry for BFSP1
1. General information
| Official gene symbol | BFSP1 |
|---|---|
| Entrez ID | 631 |
| Gene full name | beaded filament structural protein 1, filensin |
| Other gene symbols | CP115 CP94 LIFL-H |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005200 | Structural constituent of cytoskeleton | TAS | molecular_function |
| GO:0005212 | Structural constituent of eye lens | IEA | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005739 | Mitochondrion | IDA | cellular_component |
| GO:0005882 | Intermediate filament | IEA | cellular_component |
| GO:0005886 | Plasma membrane | IDA | cellular_component |
| GO:0008150 | Biological_process | ND | biological_process |
| GO:0015629 | Actin cytoskeleton | IDA | cellular_component |
| GO:0048469 | Cell maturation | IEA | biological_process |
| GO:0070307 | Lens fiber cell development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0259070590 | 0.7490284716 | 0.3765483444 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1286128944 |
| GSE13712_SHEAR | Down | -1.2155895730 |
| GSE13712_STATIC | Down | -0.6629157912 |
| GSE19018 | Up | 0.0283537487 |
| GSE19899_A1 | Up | 0.2372450329 |
| GSE19899_A2 | Up | 0.9023706116 |
| PubMed_21979375_A1 | Up | 0.8239833816 |
| PubMed_21979375_A2 | Up | 0.2571803381 |
| GSE35957 | Down | -0.1732198450 |
| GSE36640 | Up | 1.6918184691 |
| GSE54402 | Up | 0.5745883390 |
| GSE9593 | Up | 0.4994313412 |
| GSE43922 | Up | 0.2202108242 |
| GSE24585 | Up | 0.0089657149 |
| GSE37065 | Down | -0.1107912378 |
| GSE28863_A1 | Up | 0.0054172244 |
| GSE28863_A2 | Down | -0.1762959709 |
| GSE28863_A3 | Up | 0.1937919061 |
| GSE28863_A4 | Up | 0.0361897874 |
| GSE48662 | Up | 0.6249585507 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT051941 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 15849192 | These cells run into cellular senescence due to shortening of the telomeres and also commit differentiation as indicated by the accumulation of the differentiation markers, beta-crystallin and filensin |
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