HCSGD entry for S100A12

1. General information

Official gene symbolS100A12
Entrez ID6283
Gene full nameS100 calcium binding protein A12
Other gene symbolsCAAF1 CAGC CGRP ENRAGE MRP-6 MRP6 p6
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in PPI subnetwork.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002548Monocyte chemotaxisTASbiological_process
GO:0005507Copper ion bindingTASmolecular_function
GO:0005509Calcium ion bindingTASmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005634NucleusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005856CytoskeletonTAScellular_component
GO:0005886Plasma membraneTAScellular_component
GO:0006805Xenobiotic metabolic processIDAbiological_process
GO:0006954Inflammatory responseIEAbiological_process
GO:0008270Zinc ion bindingTASmolecular_function
GO:0030593Neutrophil chemotaxisTASbiological_process
GO:0031640Killing of cells of other organismIEAbiological_process
GO:0042742Defense response to bacteriumTASbiological_process
GO:0043123Positive regulation of I-kappaB kinase/NF-kappaB signalingIDAbiological_process
GO:0043406Positive regulation of MAP kinase activityTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0045576Mast cell activationTASbiological_process
GO:0050663Cytokine secretionTASbiological_process
GO:0050729Positive regulation of inflammatory responseTASbiological_process
GO:0050786RAGE receptor bindingIDA IPI TASmolecular_function
GO:0050832Defense response to fungusIDA TASbiological_process
GO:0051092Positive regulation of NF-kappaB transcription factor activityTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.34733043200.90549578280.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1003184477
GSE13712_SHEARDown-0.2599927564
GSE13712_STATICUp0.1377579891
GSE19018Up0.1629718383
GSE19899_A1Up0.0992914264
GSE19899_A2Up0.0822945224
PubMed_21979375_A1Up0.1715439684
PubMed_21979375_A2Down-0.0509000916
GSE35957Up0.1920957081
GSE36640Up0.0735417694
GSE54402Up0.0640141889
GSE9593Down-0.1633876379
GSE43922Up0.0144440569
GSE24585Up0.3005729965
GSE37065Down-0.0458069555
GSE28863_A1Down-0.0054020218
GSE28863_A2Up0.0963799746
GSE28863_A3Up0.1416492425
GSE28863_A4Up0.0920581036
GSE48662Up0.0627176827

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

OlopatadineDB00768 APRD00310
AmlexanoxDB01025 APRD00795

  • MicroRNAs

    • mirTarBase
No target information from mirTarBase
    • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.