HCSGD entry for RTN2
1. General information
| Official gene symbol | RTN2 |
|---|---|
| Entrez ID | 6253 |
| Gene full name | reticulon 2 |
| Other gene symbols | NSP2 NSPL1 NSPLI SPG12 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0014802 | Terminal cisterna | IEA | cellular_component |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030176 | Integral component of endoplasmic reticulum membrane | NAS | cellular_component |
| GO:0030315 | T-tubule | IEA | cellular_component |
| GO:0046324 | Regulation of glucose import | IEA | biological_process |
| GO:0065002 | Intracellular protein transmembrane transport | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1233689146 | 0.1437345352 | 0.7177703802 | 0.7303545753 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.7469068181 |
| GSE13712_SHEAR | Down | -0.9743659757 |
| GSE13712_STATIC | Down | -0.4676411681 |
| GSE19018 | Up | 0.2289233060 |
| GSE19899_A1 | Down | -0.2601868994 |
| GSE19899_A2 | Up | 0.2647998354 |
| PubMed_21979375_A1 | Up | 0.4142972756 |
| PubMed_21979375_A2 | Up | 0.2879144791 |
| GSE35957 | Up | 0.7647458100 |
| GSE36640 | Up | 0.9930558177 |
| GSE54402 | Down | -0.1717604496 |
| GSE9593 | Up | 0.2607811072 |
| GSE43922 | Up | 0.0494918874 |
| GSE24585 | Up | 0.6947021611 |
| GSE37065 | Down | -0.0787669749 |
| GSE28863_A1 | Down | -0.0326079069 |
| GSE28863_A2 | Down | -0.6076753906 |
| GSE28863_A3 | Up | 0.2275985935 |
| GSE28863_A4 | Down | -0.0788524972 |
| GSE48662 | Up | 0.1635342171 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018584 | Microarray | Functional MTI (Weak) | 18185580 |
| hsa-miR-375 | MIMAT0000728 | MIRT019899 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050482 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
