HCSGD entry for CLIP1
1. General information
| Official gene symbol | CLIP1 |
|---|---|
| Entrez ID | 6249 |
| Gene full name | CAP-GLY domain containing linker protein 1 |
| Other gene symbols | CLIP CLIP-170 CLIP170 CYLN1 RSN |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000278 | Mitotic cell cycle | TAS | biological_process |
| GO:0000776 | Kinetochore | TAS | cellular_component |
| GO:0001578 | Microtubule bundle formation | IMP | biological_process |
| GO:0001726 | Ruffle | IEA | cellular_component |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005768 | Endosome | TAS | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005874 | Microtubule | IEA ISS | cellular_component |
| GO:0005881 | Cytoplasmic microtubule | IEA | cellular_component |
| GO:0005882 | Intermediate filament | TAS | cellular_component |
| GO:0006810 | Transport | IEA | biological_process |
| GO:0007067 | Mitosis | TAS | biological_process |
| GO:0008017 | Microtubule binding | IDA | molecular_function |
| GO:0008270 | Zinc ion binding | IDA IEA | molecular_function |
| GO:0015630 | Microtubule cytoskeleton | IMP | cellular_component |
| GO:0015631 | Tubulin binding | IDA | molecular_function |
| GO:0030659 | Cytoplasmic vesicle membrane | IEA | cellular_component |
| GO:0031116 | Positive regulation of microtubule polymerization | IEA IMP | biological_process |
| GO:0035371 | Microtubule plus-end | IDA IEA | cellular_component |
| GO:0042803 | Protein homodimerization activity | TAS | molecular_function |
| GO:0044354 | Macropinosome | IDA | cellular_component |
| GO:0046872 | Metal ion binding | NAS | molecular_function |
| GO:0051010 | Microtubule plus-end binding | IDA IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1117778884 | 0.9511928460 | 0.6904038949 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0522880460 |
| GSE13712_SHEAR | Up | 0.4198747404 |
| GSE13712_STATIC | Up | 0.0839048805 |
| GSE19018 | Up | 0.2180218214 |
| GSE19899_A1 | Down | -0.1432169790 |
| GSE19899_A2 | Up | 0.1415327775 |
| PubMed_21979375_A1 | Up | 0.1679165266 |
| PubMed_21979375_A2 | Up | 0.0253594631 |
| GSE35957 | Up | 0.3242962520 |
| GSE36640 | Up | 0.5166612984 |
| GSE54402 | Down | -0.4178609869 |
| GSE9593 | Up | 0.1251212597 |
| GSE43922 | Down | -0.0265317373 |
| GSE24585 | Up | 0.3175251530 |
| GSE37065 | Up | 0.0528566709 |
| GSE28863_A1 | Up | 0.4236889339 |
| GSE28863_A2 | Up | 0.4126283702 |
| GSE28863_A3 | Down | -0.0105433786 |
| GSE28863_A4 | Up | 0.0467565814 |
| GSE48662 | Up | 0.1235588077 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020216 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-103a-3p | MIMAT0000101 | MIRT027105 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031181 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
