HCSGD entry for RREB1
1. General information
| Official gene symbol | RREB1 |
|---|---|
| Entrez ID | 6239 |
| Gene full name | ras responsive element binding protein 1 |
| Other gene symbols | FINB HNT LZ321 RREB-1 Zep-1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in PPI subnetwork.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | TAS | cellular_component |
| GO:0005737 | Cytoplasm | TAS | cellular_component |
| GO:0006355 | Regulation of transcription, DNA-templated | TAS | biological_process |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0007265 | Ras protein signal transduction | TAS | biological_process |
| GO:0007275 | Multicellular organismal development | TAS | biological_process |
| GO:0016604 | Nuclear body | TAS | cellular_component |
| GO:0016607 | Nuclear speck | IEA | cellular_component |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IEA | biological_process |
| GO:0045893 | Positive regulation of transcription, DNA-templated | TAS | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8998153490 | 0.5623079138 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1590356300 |
| GSE13712_SHEAR | Up | 0.0863287555 |
| GSE13712_STATIC | Up | 0.0348892378 |
| GSE19018 | Up | 0.0176200761 |
| GSE19899_A1 | Up | 0.0181318733 |
| GSE19899_A2 | Down | -0.1160484092 |
| PubMed_21979375_A1 | Down | -0.0446726839 |
| PubMed_21979375_A2 | Up | 0.0051689237 |
| GSE35957 | Down | -0.0220899155 |
| GSE36640 | Down | -0.2529846403 |
| GSE54402 | Up | 0.0354445595 |
| GSE9593 | Down | -0.1560965963 |
| GSE43922 | Up | 0.0507663353 |
| GSE24585 | Down | -0.0304801443 |
| GSE37065 | Down | -0.1290332370 |
| GSE28863_A1 | Up | 0.1634671632 |
| GSE28863_A2 | Up | 0.2129463650 |
| GSE28863_A3 | Up | 0.1356362335 |
| GSE28863_A4 | Down | -0.0974179925 |
| GSE48662 | Down | -0.1361873693 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT021051 | Proteomics;Other | Functional MTI (Weak) | 20584899 |
| hsa-miR-671-5p | MIMAT0003880 | MIRT039263 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT044319 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30d-5p | MIMAT0000245 | MIRT047790 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
- mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
